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A New Double Stranded RNA Suppresses Bladder Cancer Development by Upregulating p21(Waf1/CIP1) Expression

We have previously demonstrated that miR-1180-5p has potent ability to upregulate p21 expression by targeting promoter and inhibit bladder cancer. This prompted us to conjecture that a candidate dsRNA (dsP21-397) with perfect complementarity to the miR-1180-5p target site of p21 promoter may also tr...

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Detalles Bibliográficos
Autores principales: Wang, Chenghe, Ge, Qiangqiang, Chen, Zhong, Hu, Jia, Li, Fan, Song, Xiaodong, Xu, Hua, Ye, Zhangqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396018/
https://www.ncbi.nlm.nih.gov/pubmed/25918708
http://dx.doi.org/10.1155/2015/304753

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