Integrative Analysis of CRISPR/Cas9 Target Sites in the Human HBB Gene

Recently, the clustered regularly interspaced short palindromic repeats (CRISPR) system has emerged as a powerful customizable artificial nuclease to facilitate precise genetic correction for tissue regeneration and isogenic disease modeling. However, previous studies reported substantial off-target...

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Detalles Bibliográficos
Autores principales: Luo, Yumei, Zhu, Detu, Zhang, Zhizhuo, Chen, Yaoyong, Sun, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396065/
https://www.ncbi.nlm.nih.gov/pubmed/25918715
http://dx.doi.org/10.1155/2015/514709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396065/
https://www.ncbi.nlm.nih.gov/pubmed/25918715
http://dx.doi.org/10.1155/2015/514709

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