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Emerging Roles of Focal Adhesion Kinase in Cancer

Focal adhesion kinase (FAK) is a cytoplasmic nonreceptor tyrosine kinase that enables activation by growth factor receptors or integrins in various types of human cancers. The kinase-dependent and kinase-independent scaffolding functions of FAK modulate the authentic signaling and fundamental functi...

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Detalles Bibliográficos
Autores principales: Tai, Yu-Ling, Chen, Lih-Chyang, Shen, Tang-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396139/
https://www.ncbi.nlm.nih.gov/pubmed/25918719
http://dx.doi.org/10.1155/2015/690690