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Emerging Roles of Focal Adhesion Kinase in Cancer
Focal adhesion kinase (FAK) is a cytoplasmic nonreceptor tyrosine kinase that enables activation by growth factor receptors or integrins in various types of human cancers. The kinase-dependent and kinase-independent scaffolding functions of FAK modulate the authentic signaling and fundamental functi...
Autores principales: | Tai, Yu-Ling, Chen, Lih-Chyang, Shen, Tang-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396139/ https://www.ncbi.nlm.nih.gov/pubmed/25918719 http://dx.doi.org/10.1155/2015/690690 |
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