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Neuroendocrine Differentiation in Prostate Cancer: A Mechanism of Radioresistance and Treatment Failure
Neuroendocrine differentiation (NED) in prostate cancer is a well-recognized phenotypic change by which prostate cancer cells transdifferentiate into neuroendocrine-like (NE-like) cells. NE-like cells lack the expression of androgen receptor and prostate specific antigen, and are resistant to treatm...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396194/ https://www.ncbi.nlm.nih.gov/pubmed/25927031 http://dx.doi.org/10.3389/fonc.2015.00090 |