Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling

The impact of protein arginine methylation on the regulation of immune functions is virtually unknown. Here, we apply a novel method—isomethionine methyl-SILAC—coupled with antibody-mediated arginine-methylated peptide enrichment to identify methylated peptides in human T cells by mass spectrometry....

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Detalles Bibliográficos
Autores principales: Geoghegan, Vincent, Guo, Ailan, Trudgian, David, Thomas, Benjamin, Acuto, Oreste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396391/
https://www.ncbi.nlm.nih.gov/pubmed/25849564
http://dx.doi.org/10.1038/ncomms7758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396391/
https://www.ncbi.nlm.nih.gov/pubmed/25849564
http://dx.doi.org/10.1038/ncomms7758

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