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Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling
The impact of protein arginine methylation on the regulation of immune functions is virtually unknown. Here, we apply a novel method—isomethionine methyl-SILAC—coupled with antibody-mediated arginine-methylated peptide enrichment to identify methylated peptides in human T cells by mass spectrometry....
Autores principales: | Geoghegan, Vincent, Guo, Ailan, Trudgian, David, Thomas, Benjamin, Acuto, Oreste |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396391/ https://www.ncbi.nlm.nih.gov/pubmed/25849564 http://dx.doi.org/10.1038/ncomms7758 |
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