Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

Brain metastasis is an important cause of mortality in breast cancer patients. A key event during brain metastasis is the migration of cancer cells through blood–brain barrier (BBB). However, the molecular mechanism behind the passage through this natural barrier remains unclear. Here we show that c...

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Detalles Bibliográficos
Autores principales: Tominaga, Naoomi, Kosaka, Nobuyoshi, Ono, Makiko, Katsuda, Takeshi, Yoshioka, Yusuke, Tamura, Kenji, Lötvall, Jan, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396394/
https://www.ncbi.nlm.nih.gov/pubmed/25828099
http://dx.doi.org/10.1038/ncomms7716

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