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Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols

Background. Phenome-Wide Association Studies (PheWAS) identify genetic associations across multiple phenotypes. Clinical trials offer opportunities for PheWAS to identify pharmacogenomic associations. We describe the first PheWAS to use genome-wide genotypic data and to utilize human immunodeficienc...

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Detalles Bibliográficos
Autores principales: Moore, Carrie B., Verma, Anurag, Pendergrass, Sarah, Verma, Shefali S., Johnson, Daniel H., Daar, Eric S., Gulick, Roy M., Haubrich, Richard, Robbins, Gregory K., Ritchie, Marylyn D., Haas, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396430/
https://www.ncbi.nlm.nih.gov/pubmed/25884002
http://dx.doi.org/10.1093/ofid/ofu113