Age-associated DNA methylation changes in immune genes, histone modifiers and chromatin remodeling factors within 5 years after birth in human blood leukocytes

BACKGROUND: Age-related changes in DNA methylation occurring in blood leukocytes during early childhood may reflect epigenetic maturation. We hypothesized that some of these changes involve gene networks of critical relevance in leukocyte biology and conducted a prospective study to elucidate the dy...

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Detalles Bibliográficos
Autores principales: Acevedo, Nathalie, Reinius, Lovisa E, Vitezic, Morana, Fortino, Vittorio, Söderhäll, Cilla, Honkanen, Hanna, Veijola, Riitta, Simell, Olli, Toppari, Jorma, Ilonen, Jorma, Knip, Mikael, Scheynius, Annika, Hyöty, Heikki, Greco, Dario, Kere, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396570/
https://www.ncbi.nlm.nih.gov/pubmed/25874017
http://dx.doi.org/10.1186/s13148-015-0064-6

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