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Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib

BACKGROUNDS: Cancer stem cell (CSC) research has highlighted the necessity of developing drugs targeting CSCs. We investigated a hepatocellular carcinoma (HCC) cell line that not only has CSC hierarchy but also shows phenotypic changes (population changes) upon differentiation of CSC during culture...

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Detalles Bibliográficos
Autores principales:	Yamada, Takeshi, Abei, Masato, Danjoh, Inaho, Shirota, Ryoko, Yamashita, Taro, Hyodo, Ichinosuke, Nakamura, Yukio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396571/ https://www.ncbi.nlm.nih.gov/pubmed/25885470 http://dx.doi.org/10.1186/s12885-015-1297-7

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