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Gelatin nanoparticle-mediated intranasal delivery of substance P protects against 6-hydroxydopamine-induced apoptosis: an in vitro and in vivo study

BACKGROUND: The aim of this study was to investigate the protective role of intranasally administered substance P-loaded gelatin nanoparticles (SP-GNPs) against 6-hydroxydopamine (6-OHDA)-induced apoptosis in vitro and in vivo, and to provide a new strategy for treating brain pathology, such as Park...

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Detalles Bibliográficos
Autores principales: Lu, Cui-Tao, Jin, Rong-Rong, Jiang, Yi-Na, Lin, Qian, Yu, Wen-Ze, Mao, Kai-Li, Tian, Fu-Rong, Zhao, Ya-Ping, Zhao, Ying-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396575/
https://www.ncbi.nlm.nih.gov/pubmed/25897205
http://dx.doi.org/10.2147/DDDT.S77237