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Quinoline-based clioquinol and nitroxoline exhibit anticancer activity inducing FoxM1 inhibition in cholangiocarcinoma cells

PURPOSE: Fork head box M1 (FoxM1) is an oncogenic transcription factor frequently elevated in numerous cancers, including cholangiocarcinoma (CCA). A growing body of evidence documents its diverse functions contributing to tumorigenesis and cancer progression. As such, discovery of agents that can t...

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Detalles Bibliográficos
Autores principales:	Chan-on, Waraporn, Huyen, Nguyen Thi Bich, Songtawee, Napat, Suwanjang, Wilasinee, Prachayasittikul, Supaluk, Prachayasittikul, Virapong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396583/ https://www.ncbi.nlm.nih.gov/pubmed/25897210 http://dx.doi.org/10.2147/DDDT.S79313

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