Cargando…

Protective role of the dynamin inhibitor Dynasore against the cholesterol-dependent cytolysin of Trueperella pyogenes

The virulence of many Gram-positive bacteria depends on cholesterol-dependent cytolysins (CDCs), which form pores in eukaryotic cell plasma membranes. Pyolysin (PLO) from Trueperella pyogenes provided a unique opportunity to explore cellular responses to CDCs because it does not require thiol activa...

Descripción completa

Detalles Bibliográficos
Autores principales: Preta, Giulio, Lotti, Virginia, Cronin, James G., Sheldon, I. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396600/
https://www.ncbi.nlm.nih.gov/pubmed/25550455
http://dx.doi.org/10.1096/fj.14-265207