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Protective role of the dynamin inhibitor Dynasore against the cholesterol-dependent cytolysin of Trueperella pyogenes

The virulence of many Gram-positive bacteria depends on cholesterol-dependent cytolysins (CDCs), which form pores in eukaryotic cell plasma membranes. Pyolysin (PLO) from Trueperella pyogenes provided a unique opportunity to explore cellular responses to CDCs because it does not require thiol activa...

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Detalles Bibliográficos
Autores principales:	Preta, Giulio, Lotti, Virginia, Cronin, James G., Sheldon, I. Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2015
Materias:	Research Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396600/ https://www.ncbi.nlm.nih.gov/pubmed/25550455 http://dx.doi.org/10.1096/fj.14-265207

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