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Catechol-O-methyltransferase Val158Met genotype and the clinical responses to duloxetine treatment or plasma levels of 3-methoxy-4-hydroxyphenylglycol and homovanillic acid in Japanese patients with major depressive disorder

PURPOSE: This study investigated the relationships among the plasma levels of catecholamine metabolites, the clinical response to duloxetine treatment, and Val158Met polymorphism of the catechol-O-methyltransferase (COMT) gene. SUBJECTS AND METHODS: Sixty-four patients and 30 healthy control subject...

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Detalles Bibliográficos
Autores principales:	Atake, Kiyokazu, Yoshimura, Reiji, Hori, Hikaru, Katsuki, Asuka, Nakamura, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396648/ https://www.ncbi.nlm.nih.gov/pubmed/25897233 http://dx.doi.org/10.2147/NDT.S80953

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