Distinct Metabolomic Signatures Are Associated with Longevity in Humans

Alterations in metabolism influence lifespan in experimental models, but data in humans are lacking. Here we use liquid chromatography/mass spectrometry to quantify 217 plasma metabolites and examine their relation to longevity in a large cohort of men and women. In 647 individuals followed for up t...

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Detalles Bibliográficos
Autores principales: Cheng, Susan, Larson, Martin G., McCabe, Elizabeth L., Murabito, Joanne M., Rhee, Eugene P., Ho, Jennifer E., Jacques, Paul F., Ghorbani, Anahita, Magnusson, Martin, Souza, Amanda L., Deik, Amy A., Pierce, Kerry A., Bullock, Kevin, O’Donnell, Christopher J., Melander, Olle, Clish, Clary B., Vasan, Ramachandran S., Gerszten, Robert E., Wang, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396657/
https://www.ncbi.nlm.nih.gov/pubmed/25864806
http://dx.doi.org/10.1038/ncomms7791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396657/
https://www.ncbi.nlm.nih.gov/pubmed/25864806
http://dx.doi.org/10.1038/ncomms7791

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