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Plasticity of Hopx(+) Type I alveolar cells to regenerate Type II cells in the lung

The plasticity of differentiated cells in adult tissues undergoing repair is an area of intense research. Pulmonary alveolar Type II cells produce surfactant and function as progenitors in the adult, demonstrating both self-renewal and differentiation into gas exchanging Type I cells. In vivo, Type...

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Detalles Bibliográficos
Autores principales: Jain, Rajan, Barkauskas, Christina E., Takeda, Norifumi, Bowie, Emily J., Aghajanian, Haig, Wang, Qiaohong, Padmanabhan, Arun, Manderfield, Lauren J., Gupta, Mudit, Li, Deqiang, Li, Li, Trivedi, Chinmay M., Hogan, Brigid L. M., Epstein, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396689/
https://www.ncbi.nlm.nih.gov/pubmed/25865356
http://dx.doi.org/10.1038/ncomms7727