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Plasticity of Hopx(+) Type I alveolar cells to regenerate Type II cells in the lung
The plasticity of differentiated cells in adult tissues undergoing repair is an area of intense research. Pulmonary alveolar Type II cells produce surfactant and function as progenitors in the adult, demonstrating both self-renewal and differentiation into gas exchanging Type I cells. In vivo, Type...
Autores principales: | Jain, Rajan, Barkauskas, Christina E., Takeda, Norifumi, Bowie, Emily J., Aghajanian, Haig, Wang, Qiaohong, Padmanabhan, Arun, Manderfield, Lauren J., Gupta, Mudit, Li, Deqiang, Li, Li, Trivedi, Chinmay M., Hogan, Brigid L. M., Epstein, Jonathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396689/ https://www.ncbi.nlm.nih.gov/pubmed/25865356 http://dx.doi.org/10.1038/ncomms7727 |
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