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Structural Basis of Latrophilin-FLRT Interaction

Latrophilins, receptors for spider venom α-latrotoxin, are adhesion type G-protein-coupled receptors with emerging functions in synapse development. The N-terminal region binds the endogenous cell adhesion molecule FLRT, a major regulator of cortical and synapse development. We present crystallograp...

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Detalles Bibliográficos
Autores principales: Jackson, Verity A., del Toro, Daniel, Carrasquero, Maria, Roversi, Pietro, Harlos, Karl, Klein, Rüdiger, Seiradake, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396693/
https://www.ncbi.nlm.nih.gov/pubmed/25728924
http://dx.doi.org/10.1016/j.str.2015.01.013