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Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease

Next-generation DNA sequencing has revolutionized the field of genetics and genomics, providing researchers with the tools to efficiently identify novel rare and low frequency risk variants, which was not practical with previously available methodologies. These methods allow for the sequence capture...

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Detalles Bibliográficos
Autores principales: Wiley, Graham B, Kelly, Jennifer A, Gaffney, Patrick M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396863/
https://www.ncbi.nlm.nih.gov/pubmed/25789374
http://dx.doi.org/10.1186/s13075-014-0490-4

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