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Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease
Next-generation DNA sequencing has revolutionized the field of genetics and genomics, providing researchers with the tools to efficiently identify novel rare and low frequency risk variants, which was not practical with previously available methodologies. These methods allow for the sequence capture...
Autores principales: | Wiley, Graham B, Kelly, Jennifer A, Gaffney, Patrick M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396863/ https://www.ncbi.nlm.nih.gov/pubmed/25789374 http://dx.doi.org/10.1186/s13075-014-0490-4 |
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