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Renal Oxidative Stress Induced by Long-Term Hyperuricemia Alters Mitochondrial Function and Maintains Systemic Hypertension
We addressed if oxidative stress in the renal cortex plays a role in the induction of hypertension and mitochondrial alterations in hyperuricemia. A second objective was to evaluate whether the long-term treatment with the antioxidant Tempol prevents renal oxidative stress, mitochondrial alterations...
Autores principales: | Cristóbal-García, Magdalena, García-Arroyo, Fernando E., Tapia, Edilia, Osorio, Horacio, Arellano-Buendía, Abraham S., Madero, Magdalena, Rodríguez-Iturbe, Bernardo, Pedraza-Chaverrí, José, Correa, Francisco, Zazueta, Cecilia, Johnson, Richard J., Sánchez Lozada, Laura-Gabriela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396880/ https://www.ncbi.nlm.nih.gov/pubmed/25918583 http://dx.doi.org/10.1155/2015/535686 |
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