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Oncogenic HER2 fusions in gastric cancer
BACKGROUND: Genetic amplification of HER2 drives tumorigenesis and cancer progression in a subset of patients with gastric cancer (GC), and treatment with trastuzumab, a humanized HER2-neutralizing antibody, improves the overall survival rate of HER2-positive patients. However, a considerable portio...
Autores principales: | Yu, De-Hua, Tang, Lili, Dong, Hua, Dong, Zhengwei, Zhang, Lianhai, Fu, Jiangang, Su, Xinying, Zhang, Tianwei, Fu, Haihua, Han, Lu, Xie, Liang, Chen, Hao, Qian, Ziliang, Zhu, Guanshan, Wang, Jia, Ye, Qingqing, Zhang, Jingchuan, Yin, Xiaolu, Zhang, Xiaolin, Ji, Jiafu, Ji, Qunsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396883/ https://www.ncbi.nlm.nih.gov/pubmed/25889497 http://dx.doi.org/10.1186/s12967-015-0476-2 |
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