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Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy

Objectives. To evaluate risk factors and to develop a simple scoring system to grade the risk of postoperative hypothyroidism (PH). Methods. In a controlled prospective study, 109 patients, who underwent hemithyroidectomy for a benign thyroid disease, were followed up for 12 months. The relation bet...

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Autores principales: Beisa, Virgilijus, Kazanavicius, Darius, Skrebunas, Arminas, Simutis, Gintaras, Ivaska, Justinas, Strupas, Kestutis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396907/
https://www.ncbi.nlm.nih.gov/pubmed/25918526
http://dx.doi.org/10.1155/2015/313971
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author Beisa, Virgilijus
Kazanavicius, Darius
Skrebunas, Arminas
Simutis, Gintaras
Ivaska, Justinas
Strupas, Kestutis
author_facet Beisa, Virgilijus
Kazanavicius, Darius
Skrebunas, Arminas
Simutis, Gintaras
Ivaska, Justinas
Strupas, Kestutis
author_sort Beisa, Virgilijus
collection PubMed
description Objectives. To evaluate risk factors and to develop a simple scoring system to grade the risk of postoperative hypothyroidism (PH). Methods. In a controlled prospective study, 109 patients, who underwent hemithyroidectomy for a benign thyroid disease, were followed up for 12 months. The relation between clinical data and PH was analyzed for significance. A risk scoring system based on significant risk factors and clinical implications was developed. Results. The significant risk factors of PH were higher TSH (thyroid-stimulating hormone) level and lower ratio of the remaining thyroid weight to the patient's weight (derived weight index). Based on the log of risk factor, preoperative TSH level greater than 1.4 mU/L was assigned 2 points; 1 point was for 0.8–1.4 mU/L. The derived weight index lower than 0.8 g/kg was assigned 1 point. A risk scoring system was calculated by summing the scores. The incidences of PH were 7.3%, 30.4%, and 69.2% according to the risk scores of 0-1, 2, and 3. Conclusion. Risk factors for PH are higher preoperative TSH level and lower derived weight index. Our developed risk scoring system is a valid and reliable tool to identify patients who are at risk for PH before surgery.
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spelling pubmed-43969072015-04-27 Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy Beisa, Virgilijus Kazanavicius, Darius Skrebunas, Arminas Simutis, Gintaras Ivaska, Justinas Strupas, Kestutis Int J Endocrinol Clinical Study Objectives. To evaluate risk factors and to develop a simple scoring system to grade the risk of postoperative hypothyroidism (PH). Methods. In a controlled prospective study, 109 patients, who underwent hemithyroidectomy for a benign thyroid disease, were followed up for 12 months. The relation between clinical data and PH was analyzed for significance. A risk scoring system based on significant risk factors and clinical implications was developed. Results. The significant risk factors of PH were higher TSH (thyroid-stimulating hormone) level and lower ratio of the remaining thyroid weight to the patient's weight (derived weight index). Based on the log of risk factor, preoperative TSH level greater than 1.4 mU/L was assigned 2 points; 1 point was for 0.8–1.4 mU/L. The derived weight index lower than 0.8 g/kg was assigned 1 point. A risk scoring system was calculated by summing the scores. The incidences of PH were 7.3%, 30.4%, and 69.2% according to the risk scores of 0-1, 2, and 3. Conclusion. Risk factors for PH are higher preoperative TSH level and lower derived weight index. Our developed risk scoring system is a valid and reliable tool to identify patients who are at risk for PH before surgery. Hindawi Publishing Corporation 2015 2015-03-30 /pmc/articles/PMC4396907/ /pubmed/25918526 http://dx.doi.org/10.1155/2015/313971 Text en Copyright © 2015 Virgilijus Beisa et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Beisa, Virgilijus
Kazanavicius, Darius
Skrebunas, Arminas
Simutis, Gintaras
Ivaska, Justinas
Strupas, Kestutis
Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy
title Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy
title_full Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy
title_fullStr Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy
title_full_unstemmed Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy
title_short Prospective Analysis of Risk for Hypothyroidism after Hemithyroidectomy
title_sort prospective analysis of risk for hypothyroidism after hemithyroidectomy
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396907/
https://www.ncbi.nlm.nih.gov/pubmed/25918526
http://dx.doi.org/10.1155/2015/313971
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