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CopywriteR: DNA copy number detection from off-target sequence data

Current methods for detection of copy number variants (CNV) and aberrations (CNA) from targeted sequencing data are based on the depth of coverage of captured exons. Accurate CNA determination is complicated by uneven genomic distribution and non-uniform capture efficiency of targeted exons. Here we...

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Detalles Bibliográficos
Autores principales:	Kuilman, Thomas, Velds, Arno, Kemper, Kristel, Ranzani, Marco, Bombardelli, Lorenzo, Hoogstraat, Marlous, Nevedomskaya, Ekaterina, Xu, Guotai, de Ruiter, Julian, Lolkema, Martijn P, Ylstra, Bauke, Jonkers, Jos, Rottenberg, Sven, Wessels, Lodewyk F, Adams, David J, Peeper, Daniel S, Krijgsman, Oscar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396974/ https://www.ncbi.nlm.nih.gov/pubmed/25887352 http://dx.doi.org/10.1186/s13059-015-0617-1

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