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Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process

The proliferation of vascular smooth muscle cells (VSMCs) is one of the main features of atherosclerosis induced by high glucose. Mevalonate pathway is an important metabolic pathway that plays a key role in multiple cellular processes. The aim of this study was to define whether the enzyme expressi...

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Detalles Bibliográficos
Autores principales: Chen, Guo-Ping, Zhang, Xiao-Qin, Wu, Tao, Li, Liang, Han, Jie, Du, Chang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396976/
https://www.ncbi.nlm.nih.gov/pubmed/25918730
http://dx.doi.org/10.1155/2015/379287