Cargando…

Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction

Chronic obstructive lung disease determines morbidity and mortality of patients with cystic fibrosis (CF). CF airways are characterized by a nonresolving neutrophilic inflammation. After pathogen contact or prolonged activation, neutrophils release DNA fibres decorated with antimicrobial proteins, f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marcos, Veronica, Zhou-Suckow, Zhe, Önder Yildirim, Ali, Bohla, Alexander, Hector, Andreas, Vitkov, Ljubomir, Krautgartner, Wolf Dietrich, Stoiber, Walter, Griese, Matthias, Eickelberg, Oliver, Mall, Marcus A., Hartl, Dominik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397025/ https://www.ncbi.nlm.nih.gov/pubmed/25918476 http://dx.doi.org/10.1155/2015/408935

Ejemplares similares

The Initial Inflammatory Response to Bioactive Implants Is Characterized by NETosis
por: Vitkov, Ljubomir, et al.
Publicado: (2015)

New Aspects on the Structure of Neutrophil Extracellular Traps from Chronic Obstructive Pulmonary Disease and In Vitro Generation
por: Obermayer, Astrid, et al.
Publicado: (2014)

The Chitinase-Like Protein YKL-40 Modulates Cystic Fibrosis Lung Disease
por: Hector, Andreas, et al.
Publicado: (2011)

Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation
por: Grabcanovic-Musija, Fikreta, et al.
Publicado: (2015)

Janus-Faced Neutrophil Extracellular Traps in Periodontitis
por: Vitkov, Ljubomir, et al.
Publicado: (2017)

The Role of Reactive Oxygen Species (ROS) in the Formation of Extracellular Traps (ETs) in Humans
por: Stoiber, Walter, et al.
Publicado: (2015)

Genetic Deletion of Mmp9 Does Not Reduce Airway Inflammation and Structural Lung Damage in Mice with Cystic Fibrosis-like Lung Disease
por: Wagner, Claudius, et al.
Publicado: (2022)

Editorial: Oral neutrophils - the good, the bad, and the ugly
por: Vitkov, Ljubomir, et al.
Publicado: (2023)

The effect of decongestion on nasal airway patency and airflow
por: Xiao, Qiwei, et al.
Publicado: (2021)

DMBT1 is upregulated in cystic fibrosis, affects ciliary motility, and is reduced by acetylcysteine
por: Kiefer, Alexander, et al.
Publicado: (2022)

Genetic Deletion and Pharmacological Inhibition of PI3Kγ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease
por: Galluzzo, Maria, et al.
Publicado: (2015)

New Developments in Cystic Fibrosis Airway Inflammation
por: Palaniyar, Nades, et al.
Publicado: (2015)

Airflow and Particle Transport Prediction through Stenosis Airways
por: Singh, Parth, et al.
Publicado: (2020)

Current concepts: host–pathogen interactions in cystic fibrosis airways disease
por: Tang, Anthony C., et al.
Publicado: (2014)

Relationship between airway inflammation and airflow limitation in elderly asthmatics
por: Soma, Tomoyuki, et al.
Publicado: (2020)

Update on host-pathogen interactions in cystic fibrosis lung disease
por: Hector, Andreas, et al.
Publicado: (2016)

Interstitial lung disease in children – genetic background and associated phenotypes
por: Hartl, Dominik, et al.
Publicado: (2005)

Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease
por: Fantino, Emmanuelle, et al.
Publicado: (2014)

Small airway determinants of airflow limitation in chronic obstructive pulmonary disease
por: Polosukhin, Vasiliy V, et al.
Publicado: (2021)

NETs Are Double-Edged Swords with the Potential to Aggravate or Resolve Periodontal Inflammation
por: Vitkov, Ljubomir, et al.
Publicado: (2020)

In Vitro Inhibition of Neutrophil Elastase Activity by Inhaled Anti-Pseudomonas Antibiotics Used in Cystic Fibrosis Patients
por: Hector, Andreas, et al.
Publicado: (2010)

Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases
por: Marcos, Veronica, et al.
Publicado: (2010)

Numerical analysis of airflow alteration in central airways following tracheobronchial stent placement
por: Ho, Chien-Yi, et al.
Publicado: (2012)

Delay of airway epithelial wound repair in COPD is associated with airflow obstruction severity
por: Perotin, Jeanne-Marie, et al.
Publicado: (2014)

Airway wall thickness and airflow limitations in asthma assessed in quantitative computed tomography
por: Patyk, Mateusz, et al.
Publicado: (2020)

Numerical and Experimental Analysis of Inhalation Airflow Dynamics in a Human Pharyngeal Airway
por: Fan, Yaming, et al.
Publicado: (2020)

Fixed Airflow Obstruction in Asthma: A Problem of the Whole Lung Not of Just the Airways
por: Rutting, Sandra, et al.
Publicado: (2022)

The effect of posture on airflow distribution, airway geometry and air velocity in healthy subjects
por: Ides, Kris M., et al.
Publicado: (2022)

Lumacaftor/ Ivacaftor improves exercise tolerance in patients with Cystic Fibrosis and severe airflow obstruction
por: Wark, Peter A. B., et al.
Publicado: (2019)

Methacholine-Induced Variations in Airway Volume and the Slope of the Alveolar Capnogram Are Distinctly Associated with Airflow Limitation and Airway Closure
por: Plantier, Laurent, et al.
Publicado: (2015)

Mouse Nuclear Myosin I Knock-Out Shows Interchangeability and Redundancy of Myosin Isoforms in the Cell Nucleus
por: Venit, Tomáš, et al.
Publicado: (2013)

522 Association between Eosinophilic Airway Inflammation and Persistent Airflow Limitation in Asthmatic Children
por: Lee, Yong Ju, et al.
Publicado: (2012)

Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction
por: Mahmood, Malik Quasir, et al.
Publicado: (2015)

Pale nasal mucosa affects airflow limitations in upper and lower airways in asthmatic children
por: Motomura, Chikako, et al.
Publicado: (2016)

Computational Fluid Dynamics Modeling of Respiratory Airflow in Tracheobronchial Airways of Infant, Child, and Adult
por: Tsega, Endalew Getnet
Publicado: (2018)

LES study on the impact of airway deformation on the airflow structures in the idealized mouth–throat model
por: Wang, Li, et al.
Publicado: (2021)

Periodontitis-Derived Dark-NETs in Severe Covid-19
por: Vitkov, Ljubomir, et al.
Publicado: (2022)

Steroid insensitive fixed airflow obstruction is not related to airway inflammation in older non-smokers with asthma
por: Tonga, K. O., et al.
Publicado: (2018)

Patients Treated for Central Airway Stenosis After Lung Transplantation Have Persistent Airflow Limitation
por: Mazzetta, Andrea, et al.
Publicado: (2019)

Airflow obstruction and small airway dysfunction following pulmonary tuberculosis: a cross-sectional survey
por: Xing, Zhenzhen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9808smp5pmimgre2qphue1gukk