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Structural Determinants of Phenotypic Diversity and Replication Rate of Human Prions

The infectious pathogen responsible for prion diseases is the misfolded, aggregated form of the prion protein, PrP(Sc). In contrast to recent progress in studies of laboratory rodent-adapted prions, current understanding of the molecular basis of human prion diseases and, especially, their vast phen...

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Detalles Bibliográficos
Autores principales:	Safar, Jiri G., Xiao, Xiangzhu, Kabir, Mohammad E., Chen, Shugui, Kim, Chae, Haldiman, Tracy, Cohen, Yvonne, Chen, Wei, Cohen, Mark L., Surewicz, Witold K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397081/ https://www.ncbi.nlm.nih.gov/pubmed/25875953 http://dx.doi.org/10.1371/journal.ppat.1004832

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