Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate

Carcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case...

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Autores principales: Dudani, Sharmila, Malik, Ajay, Sandhu, A. S., Mani, N. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397551/
https://www.ncbi.nlm.nih.gov/pubmed/25878416
http://dx.doi.org/10.4103/0970-1591.152921
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author Dudani, Sharmila
Malik, Ajay
Sandhu, A. S.
Mani, N. S.
author_facet Dudani, Sharmila
Malik, Ajay
Sandhu, A. S.
Mani, N. S.
author_sort Dudani, Sharmila
collection PubMed
description Carcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case of α-methyl–CoA-racemase (AMACR)-negative pseudohyperplastic variant of adenocarcinoma in CS. To the best of our knowledge, there have been no published case reports of this variant in CS till date. An accurate diagnosis is essential as this uncommon, aggressive cancer has limited therapeutic options
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spelling pubmed-43975512015-04-15 Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate Dudani, Sharmila Malik, Ajay Sandhu, A. S. Mani, N. S. Indian J Urol Case Report Carcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case of α-methyl–CoA-racemase (AMACR)-negative pseudohyperplastic variant of adenocarcinoma in CS. To the best of our knowledge, there have been no published case reports of this variant in CS till date. An accurate diagnosis is essential as this uncommon, aggressive cancer has limited therapeutic options Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4397551/ /pubmed/25878416 http://dx.doi.org/10.4103/0970-1591.152921 Text en Copyright: © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dudani, Sharmila
Malik, Ajay
Sandhu, A. S.
Mani, N. S.
Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate
title Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate
title_full Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate
title_fullStr Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate
title_full_unstemmed Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate
title_short Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–CoA-racemase (AMACR negative) carcinosarcoma of the prostate
title_sort pseudohyperplastic variant of adenocarcinoma as a component of α-methyl–coa-racemase (amacr negative) carcinosarcoma of the prostate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397551/
https://www.ncbi.nlm.nih.gov/pubmed/25878416
http://dx.doi.org/10.4103/0970-1591.152921
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AT sandhuas pseudohyperplasticvariantofadenocarcinomaasacomponentofamethylcoaracemaseamacrnegativecarcinosarcomaoftheprostate
AT manins pseudohyperplasticvariantofadenocarcinomaasacomponentofamethylcoaracemaseamacrnegativecarcinosarcomaoftheprostate

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