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Gene polymorphisms in RANKL/RANK/OPG pathway are associated with ages at menarche and natural menopause in Chinese women

BACKGROUND: Age at menarche (AAM) and age at natural menopause (AANM) have been shown intimately associated with woman’s health later in life. Previous studies have indicated that AAM and AANM are highly heritable. RANKL/RANK/OPG signaling pathway is essential for mammary gland development, which is...

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Detalles Bibliográficos
Autores principales: Duan, Peng, Wang, Zhi-Ming, Liu, Jiang, Wang, Li-Na, Yang, Zhi, Tu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397679/
https://www.ncbi.nlm.nih.gov/pubmed/25884698
http://dx.doi.org/10.1186/s12905-015-0192-3