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TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models

BACKGROUND: The innate immune response plays an important role in the pathogenesis of intracerebral hemorrhage (ICH). Recent studies have shown that Toll-like receptor 2 (TLR2) is involved in the innate immune response in various neurological diseases, yet neither its role in ICH nor the mechanisms...

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Detalles Bibliográficos
Autores principales:	Min, Hyunjung, Hong, Jinpyo, Cho, Ik-Hyun, Jang, Yong Ho, Lee, Hyunkyoung, Kim, Dongwoon, Yu, Seong-Woon, Lee, Soojin, Lee, Sung Joong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397689/ https://www.ncbi.nlm.nih.gov/pubmed/25879213 http://dx.doi.org/10.1186/s13041-015-0116-z

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