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Immune cell-based screening assay for response to anticancer agents: applications in pharmacogenomics

BACKGROUND: Interpatient variability in immune and chemotherapeutic cytotoxic responses is likely due to complex genetic differences and is difficult to ascertain in humans. Through the use of a panel of genetically diverse mouse inbred strains, we developed a drug screening platform aimed at examin...

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Detalles Bibliográficos
Autores principales:	Frick, Amber, Fedoriw, Yuri, Richards, Kristy, Damania, Blossom, Parks, Bethany, Suzuki, Oscar, Benton, Cristina S, Chan, Emmanuel, Thomas, Russell S, Wiltshire, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397719/ https://www.ncbi.nlm.nih.gov/pubmed/25897258 http://dx.doi.org/10.2147/PGPM.S73312

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