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Retinoic acid promotes myogenesis in myoblasts by antagonizing transforming growth factor-beta signaling via C/EBPβ

BACKGROUND: The effects of transforming growth factor-beta (TGFβ) are mediated by the transcription factors Smad2 and Smad3. During adult skeletal myogenesis, TGFβ signaling inhibits the differentiation of myoblasts, and this can be reversed by treatment with retinoic acid (RA). In mesenchymal stem...

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Detalles Bibliográficos
Autores principales:	Lamarche, Émilie, Lala-Tabbert, Neena, Gunanayagam, Angelo, St-Louis, Catherine, Wiper-Bergeron, Nadine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397812/ https://www.ncbi.nlm.nih.gov/pubmed/25878769 http://dx.doi.org/10.1186/s13395-015-0032-z

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