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The metabotropic glutamate receptor 5 role on motor behavior involves specific neural substrates

BACKGROUND: The metabotropic glutamate receptor 5 (mGluR5) is involved in various brain functions, including memory, cognition and motor behavior. Regarding locomotor activity, we and others have demonstrated that pharmacological antagonism of mGluR5 promotes hyperkinesia in mice. Moreover, increase...

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Detalles Bibliográficos
Autores principales: Guimaraes, Isabella M, Carvalho, Toniana G, Ferguson, Stephen SG, Pereira, Grace S, Ribeiro, Fabiola M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397819/
https://www.ncbi.nlm.nih.gov/pubmed/25885370
http://dx.doi.org/10.1186/s13041-015-0113-2