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The metabotropic glutamate receptor 5 role on motor behavior involves specific neural substrates
BACKGROUND: The metabotropic glutamate receptor 5 (mGluR5) is involved in various brain functions, including memory, cognition and motor behavior. Regarding locomotor activity, we and others have demonstrated that pharmacological antagonism of mGluR5 promotes hyperkinesia in mice. Moreover, increase...
Autores principales: | Guimaraes, Isabella M, Carvalho, Toniana G, Ferguson, Stephen SG, Pereira, Grace S, Ribeiro, Fabiola M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397819/ https://www.ncbi.nlm.nih.gov/pubmed/25885370 http://dx.doi.org/10.1186/s13041-015-0113-2 |
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