Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3

BACKGROUND: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that acts through a family of five G-protein-coupled receptors (S1PR(1–5)) and plays a key role in regulating the inflammatory response. Our previous studies demonstrated that rat sensory neurons express the mRNAs for all five S1P...

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Detalles Bibliográficos
Autores principales: Li, Chao, Li, Jun-nan, Kays, Joanne, Guerrero, Miguel, Nicol, Grant D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397880/
https://www.ncbi.nlm.nih.gov/pubmed/25880547
http://dx.doi.org/10.1186/s12974-015-0286-8

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