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Bayesian transcriptome assembly

RNA sequencing allows for simultaneous transcript discovery and quantification, but reconstructing complete transcripts from such data remains difficult. Here, we introduce Bayesembler, a novel probabilistic method for transcriptome assembly built on a Bayesian model of the RNA sequencing process. U...

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Detalles Bibliográficos
Autores principales: Maretty, Lasse, Sibbesen, Jonas Andreas, Krogh, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397945/
https://www.ncbi.nlm.nih.gov/pubmed/25367074
http://dx.doi.org/10.1186/s13059-014-0501-4

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