MK591, a Second Generation Leukotriene Biosynthesis Inhibitor, Prevents Invasion and Induces Apoptosis in the Bone-Invading C4-2B Human Prostate Cancer Cells: Implications for the Treatment of Castration-Resistant, Bone-Metastatic Prostate Cancer

Castration-resistant prostate cancer (CRPC) is a major clinical challenge for which no cure is currently available primarily because of the lack of proper understanding about appropriate molecular target(s). Previously we observed that inhibition of 5-lipoxygenase (5-Lox) activity induces apoptosis...

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Detalles Bibliográficos
Autores principales: Sarveswaran, Sivalokanathan, Ghosh, Ritisha, Morisetty, Shravan, Ghosh, Jagadananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398363/
https://www.ncbi.nlm.nih.gov/pubmed/25875826
http://dx.doi.org/10.1371/journal.pone.0122805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398363/
https://www.ncbi.nlm.nih.gov/pubmed/25875826
http://dx.doi.org/10.1371/journal.pone.0122805

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