Deregulation between miR-29b/c and DNMT3A Is Associated with Epigenetic Silencing of the CDH1 Gene, Affecting Cell Migration and Invasion in Gastric Cancer

The de-regulation of the miR-29 family and DNA methyltransferase 3A (DNMT3A) is associated with gastric cancer (GC). While increasing evidence indicates miR-29b/c could regulate DNA methylation by targeting DNMT3A, it is currently unknown if epigenetic silencing of miR-29b/c via promoter hypermethyl...

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Detalles Bibliográficos
Autores principales: Cui, He, Wang, Ling, Gong, Pihai, Zhao, Chengcheng, Zhang, Shaodan, Zhang, Kun, Zhou, Rongping, Zhao, Zhujiang, Fan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398372/
https://www.ncbi.nlm.nih.gov/pubmed/25874772
http://dx.doi.org/10.1371/journal.pone.0123926

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