A Functional Dissection of PTEN N-Terminus: Implications in PTEN Subcellular Targeting and Tumor Suppressor Activity

Spatial regulation of the tumor suppressor PTEN is exerted through alternative plasma membrane, cytoplasmic, and nuclear subcellular locations. The N-terminal region of PTEN is important for the control of PTEN subcellular localization and function. It contains both an active nuclear localization si...

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Detalles Bibliográficos
Autores principales: Gil, Anabel, Rodríguez-Escudero, Isabel, Stumpf, Miriam, Molina, María, Cid, Víctor J., Pulido, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398541/
https://www.ncbi.nlm.nih.gov/pubmed/25875300
http://dx.doi.org/10.1371/journal.pone.0119287

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