Dysbiosis caused by vitamin D receptor deficiency confers colonization resistance to Citrobacter rodentium through modulation of innate lymphoid cells

Vitamin D receptor (VDR) knockout (KO) mice had fewer Citrobacter rodentium in the feces than wild-type (WT) mice and the kinetics of clearance was faster in VDR KO than WT mice. VDR KO mice had more IL-22 producing innate lymphoid cells (ILC), and more anti-bacterial peptides than WT mice. The incr...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Waddell, Amanda, Lin, Yang-Ding, Cantorna, Margherita T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398576/
https://www.ncbi.nlm.nih.gov/pubmed/25315967
http://dx.doi.org/10.1038/mi.2014.94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398576/
https://www.ncbi.nlm.nih.gov/pubmed/25315967
http://dx.doi.org/10.1038/mi.2014.94

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