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miR-1269 Promotes Metastasis and Forms a Positive Feedback Loop with TGF-β
As patient survival drops precipitously from early-stage cancers to late-stage and metastatic cancers, microRNAs that promote relapse and metastasis can serve as prognostic and predictive markers as well as therapeutic targets for chemoprevention. Here we show that miR-1269a promotes colorectal canc...
Autores principales: | Bu, Pengcheng, Wang, Lihua, Chen, Kai-Yuan, Rakhilin, Nikolai, Sun, Jian, Closa, Adria, Tung, Kuei-Ling, King, Sarah, Varanko, Anastasia Kristine, Xu, Yitian, Chen, Joyce Huan, Zessin, Amelia S, Shealy, James, Cummings, Bethany, Hsu, David, Lipkin, Steven M., Moreno, Victor, Gümüş, Zeynep H., Shen, Xiling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399006/ https://www.ncbi.nlm.nih.gov/pubmed/25872451 http://dx.doi.org/10.1038/ncomms7879 |
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