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Loss of AF-6/afadin induces cell invasion, suppresses the formation of glandular structures and might be a predictive marker of resistance to chemotherapy in endometrial cancer

BACKGROUND: AF-6/afadin plays an important role in the formation of adherence junctions. In breast and colon cancer, loss of AF-6/afadin induces cell migration and cell invasion. We aimed to elucidate the role of AF-6/afadin in human endometrial cancer. METHODS: Morphology and AF-6/afadin expression...

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Detalles Bibliográficos
Autores principales:	Yamamoto, Takuro, Mori, Taisuke, Sawada, Morio, Matsushima, Hiroshi, Ito, Fumitake, Akiyama, Makoto, Kitawaki, Jo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399104/ https://www.ncbi.nlm.nih.gov/pubmed/25879875 http://dx.doi.org/10.1186/s12885-015-1286-x

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