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Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains

BACKGROUND: Combined antiretroviral therapy has drastically reduced mortality and morbidity of HIV-infected individuals. Nevertheless long-term toxicity and appearance of viral resistance hampers the prolonged effectiveness of combination therapy, requiring a continuous input of drugs to replace tho...

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Detalles Bibliográficos
Autores principales:	Sironi, Francesca, Malnati, Mauro, Mongelli, Nicola, Cozzi, Paolo, Guzzo, Christina, Ghezzi, Silvia, Martínez-Romero, Carles, García-Sastre, Adolfo, Lusso, Paolo, Jabes, Daniela, Biswas, Priscilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399250/ https://www.ncbi.nlm.nih.gov/pubmed/25888743 http://dx.doi.org/10.1186/s12967-015-0461-9

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