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Genomic variant representation in a Chlamydia population is dynamic and adaptive with dependence on in vitro and in vivo passage

We have previously shown that Chlamydia muridarum has multiple genomic variants that concomitantly vary in their in vitro and in vivo phenotype. Herein, we used real-time polymerase chain reaction-based genotyping assays to query plaque-cloned isolates of C. muridarum for the frequency of eight sele...

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Detalles Bibliográficos
Autores principales: Jasper, Deana K., Sigar, Ira M., Schripsema, Justin H., Sainvil, Carlyn K., Smith, Christopher L., Yeruva, Laxmi, Rank, Roger G., Murthy, Ashlesh K., Widder, Jared R., Ramsey, Kyle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399565/
https://www.ncbi.nlm.nih.gov/pubmed/25673672
http://dx.doi.org/10.1093/femspd/ftv003