Synthetic lethals in HIV: ways to avoid drug resistance: Running title: Preventing HIV resistance

BACKGROUND: RNA viruses rapidly accumulate genetic variation, which can give rise to synthetic lethal (SL) and deleterious (SD) mutations. Synthetic lethal mutations (non-lethal when alone but lethal when combined in one genome) have been studied to develop cancer therapies. This principle can also...

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Detalles Bibliográficos
Autores principales: Petitjean, Michel, Badel, Anne, Veitia, Reiner A, Vanet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399722/
https://www.ncbi.nlm.nih.gov/pubmed/25888435
http://dx.doi.org/10.1186/s13062-015-0044-y

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