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Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathway

BACKGROUND: Cyclin D1 and its kinase partners control cell cycle progression. Cyclin D1 is frequently deregulated in various cancers, including malignant hemopathies, and tumor cells display uncontrolled cell proliferation. Cyclin D1 is not expressed in the B-cell lineage but is found in multiple my...

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Detalles Bibliográficos
Autores principales:	Bustany, Sophie, Cahu, Julie, Guardiola, Philippe, Sola, Brigitte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399746/ https://www.ncbi.nlm.nih.gov/pubmed/25881299 http://dx.doi.org/10.1186/s12885-015-1240-y

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