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Viral Inhibition of the Transporter Associated with Antigen Processing (TAP): A Striking Example of Functional Convergent Evolution

Herpesviruses are large DNA viruses that are highly abundant within their host populations. Even in the presence of a healthy immune system, these viruses manage to cause lifelong infections. This persistence is partially mediated by the virus entering latency, a phase of infection characterized by...

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Detalles Bibliográficos
Autores principales: Verweij, Marieke C., Horst, Daniëlle, Griffin, Bryan D., Luteijn, Rutger D., Davison, Andrew J., Ressing, Maaike E., Wiertz, Emmanuel J. H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399834/
https://www.ncbi.nlm.nih.gov/pubmed/25880312
http://dx.doi.org/10.1371/journal.ppat.1004743