Probing the Run-On Oligomer of Activated SgrAI Bound to DNA

SgrAI is a type II restriction endonuclease with an unusual mechanism of activation involving run-on oligomerization. The run-on oligomer is formed from complexes of SgrAI bound to DNA containing its 8 bp primary recognition sequence (uncleaved or cleaved), and also binds (and thereby activates for...

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Santosh, Sanchez, Jonathan, Stewart, Andrew, Piperakis, Michael M., Cosstick, Richard, Nichols, Claire, Park, Chad K., Ma, Xin, Wysocki, Vicki, Bitinaite, Jurate, Horton, Nancy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399878/
https://www.ncbi.nlm.nih.gov/pubmed/25880668
http://dx.doi.org/10.1371/journal.pone.0124783

Ejemplares similares

Ejemplares similares