Cardiac Safety of Modified Vaccinia Ankara for Vaccination against Smallpox in a Young, Healthy Study Population

BACKGROUND: Conventional smallpox vaccines based on replicating vaccinia virus (VV) strains (e.g. Lister Elstree, NYCBOH) are associated with a high incidence of myo-/pericarditis, a severe inflammatory cardiac complication. A new smallpox vaccine candidate based on a non-replicating Modified Vaccin...

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Detalles Bibliográficos
Autores principales: Zitzmann-Roth, Eva-Maria, von Sonnenburg, Frank, de la Motte, Stephan, Arndtz-Wiedemann, Nathaly, von Krempelhuber, Alfred, Uebler, Nadine, Vollmar, Jens, Virgin, Garth, Chaplin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399887/
https://www.ncbi.nlm.nih.gov/pubmed/25879867
http://dx.doi.org/10.1371/journal.pone.0122653

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